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Human growth hormone variants

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专利名称:Human growth hormone variants发明人:BRIAN C. CUNNINGHAM,HENRY B.

LOWMAN,JAMES A WELLS,ROSS G

CLARK,KENNETH OLSON,GERMAINE G. FUH

申请号:AU7073396申请日:19960920公开号:AU718439B2公开日:20000413

摘要:Human growth hormone variants are disclosed having enhanced affinity for thegrowth hormone receptor. Also disclosed are human growth hormone variantsconjugated to one or more chemical groups, such as poly(ethylene glycol), which isbelieved to prolong the in vivo half-life of the variants.

申请人:GENENTECH, INC.

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