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INDAZOLE DERIVATIVES AS JNK INHIBITORS

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专利名称:INDAZOLE DERIVATIVES AS JNK INHIBITORS发明人:BHAGWAT, SHRIPAD, S.,SATOH,

YOSHITAKA,SAKATA, STEVEN, T.,BUHR,CHRIS, A.,ALBERS, RONALD,SAPIENZA,JOHN,PLANTEVIN, VERONIQUE,CHAO,QI,SAHASRABUDHE, KIRAN,FERRI, RACHEL

申请号:US2004011958申请日:20040416

公开号:WO2004094388A3公开日:20041209

摘要:This invention is generally directed to Indazole Derivatives having the followingstructure (I) or pharmaceutically acceptable salt thereof, wherein R1, R2 and A are asdefined herein. Such compounds have utility in the treatment of a wide range of diseasesand disorders that are responsive to JNK inhibition, such as an inflammatory disease ordisorder. Thus, methods of treating such diseases and disorders are also disclosed, as arepharmaceutical compositions containing one or more compounds of the abovecompounds.

申请人:SIGNAL PHARMACEUTICALS, LLC,BHAGWAT, SHRIPAD, S.,SATOH,YOSHITAKA,SAKATA, STEVEN, T.,BUHR, CHRIS, A.,ALBERS, RONALD,SAPIENZA,JOHN,PLANTEVIN, VERONIQUE,CHAO, QI,SAHASRABUDHE, KIRAN,FERRI, RACHEL

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