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专利名称：Parallel polymorphism scoring by
amplification and error correction
发明人：Yan Wang,Michael Finney,Fan Chen申请号：US11521754申请日：20060915
公开号：US20070009954A1公开日：20070111
摘要：This invention provides a method of detecting polymorphisms, e.g., singlenucleotide polymorphisms (SNPs), by amplification and error correction. The inventionencompasses methods of performing amplification and error correction using an
improved generation of nucleic acid polymerases, and methods of multiplexing the assay.The improvement to the polymerases is the joining of a sequence-non-specific nucleic-acid-binding domain to the enzyme in a manner that enhances the ability of the enzymeto bind and catalytically modify the nucleic acid.
申请人：Yan Wang,Michael Finney,Fan Chen
地址：San Francisco CA US,San Francisco CA US,Alameda CA US
国籍：US,US,US
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